Lasers for Rejuvenation: "Are Some People "Non-Responders"

Research on Science of Cosmetic Lasers

Lasers for Rejuvenation: "Are Some People "Non-Responders"

PostPosted by DCNGA » Sat Jan 21, 2012 4:26 pm

If you can be a non-responder, might some people also be 'over-responders' thus their skin is damaged? You would think that researchers would want to know this as well rather than worrying about how 'successful' they can say a device will be in laser rejuvenation:

From 2006: http://www.skinandaging.com/supplements ... ersies.pdf

Could Some People be Non-Responders?

Could there be one or more temperature dependent variants in collagen and/or elastic tissue or a temperature-dependent variable in the systems responsible for the production of cytokines and other variables such as heat shock proteins such that some individuals respond well to a given thermal load administered in a standard, non-ablative treatment? Or, could apparently similar individuals have protein structures or other biological subsystems that are relatively thermal-stable with the range of thermal loads imposed during typical non-ablative treatment and so they’re poor responders?

Could there be some individuals whose recurrent regenerative processes are called into action by a moderate thermal insult of the type that we ordinarily give, while other, similar-appearing people are thermal-stable or even thermal-resistant or are thermophiles and are condemned to existence as non-responders? If the above speculations prove to be clinically relevant, perhaps some day we will have a set of genetic probes or other markers.
"It is a good thing to learn caution from the misfortunes of others."

"If you wish to succeed in life, make perseverance your bosom friend, experience your wise counselor, caution your elder brother, and hope your guardian genius."
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